Professor William Rosenberg

Job title

Professor of hepatology

Qualifications

MA, MBBS, DPhil, FRCP

GMC Number

2839989

Contact details

Phone number: 020 7794 0500 ext 31157

Email address: william.rosenberg@nhs.net

Related services

Liver services

Biography

William Rosenberg holds the Peter Scheuer Chair in Liver Diseases at UCL and is honorary consultant at the Sheila Sherlock Liver Centre. He is deputy medical director of the National Institute for Health and Care Research Clinical Research Network. His main field of practice is in viral hepatitis and his research encompasses viral hepatitis and diagnostic strategies in liver disease.

Publications

  • Petersen JR, Stevenson HL, Snyder N, Kasturi KS, Naniwadekar A, Parkes J, Cross R, Rosenberg WM, Xiao S-Y. (2014). Evaluation of the aspartate aminotransferase/platelet ratio index and enhanced liver fibrosis tests to detect significant fibrosis due to chronic hepatitis C. Journal of Clinical Gastroenterology, 48 (4), 370-376. doi:10.1097/MCG.0b013e3182a87e78
  • Macartney MJ, Irish D, Bridge SH, Garcia-Diaz A, Booth CL, McCormick AL, Labett W, Smith C, Velazquez C, Tanwar S, Trembling P, Jacobs M, Dusheiko G, Rosenberg W, Haque T. (2014). Telaprevir or Boceprevir Based Therapy for Chronic Hepatitis C Infection: Development of Resistance Associated Variants in Treatment Failure. Antiviral Res. doi:10.1016/j.antiviral.2014.02.019
  • Abignano, G., Buch, M. H., Emery, P., Del Galdo, F., Cuomo, G., Valentini, G., & Rosenberg, W. M. (2014). The enhanced liver fibrosis test: A clinical grade, validated serum test, biomarker of overall fibrosis in systemic sclerosis. Annals of the Rheumatic Diseases, 73 (2), 420-427. doi:10.1136/annrheumdis-2012-202843
  • Tedder RS, Rodger AJ, Fries L, Ijaz S, Thursz M, Rosenberg W, et al. The diversity and management of chronic Hepatitis B virus infections in the United Kingdom: a wake-up call. Clinical Infectious Diseases: an official publication of the Infectious Diseases Society of America. 2013. Epub 2012/12/12.
  • Rosenberg, W. M., Tanwar, S., & Trembling, P. (2013). Complexities of HCV management in the new era of direct-acting antiviral agents. QJM. doi:10.1093/qjmed/hct181
  • Tanwar S, Trembling PM, Guha IN, Parkes J, Kaye P, Burt AD, Rosenberg W, et al. Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease. Hepatology (Baltimore, Md). 2013;57(1):103-11.
  • Macdonald DC, Singh H, Whelan MA, Escors D, Arce F, Bottoms SE, Barclay W.S, Maini M, Collins MK, Rosenberg W.M.C. Harnessing alveolar macrophages for sustained mucosal t-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease. Mucosal Immunology. 2013. Epub 2013/05/30.
  • Trembling PM, Lampertico P, Parkes J, Tanwar S, Vigan M, Facchetti F, Rosenberg W., et al. Performance of enhanced liver fibrosis test and comparison with transient elastography in the identification of liver fibrosis in patients with chronic Hepatitis B infection. Journal of viral hepatitis. 2013:n/a-n/a.        
  • Ferenci, P., Czlonkowska, A., Stremmel, W., Houwen, R., Rosenberg, W.M., Schilsky, M., Jansen, P., Moradpour, D., Gitlin, J.,EASL Clinical Practice Guidelines: Wilson's disease. Journal of Hepatology. 2012; 56(3):671-85.            
  • Schurich, A., Pallett, l.J., Lubowiecki, M., Singh, H.D., Gill, U.S., Kennedy, P., Nastouli, E., Tanwar, S., Rosenberg, W.M., Maini, M.K. The Third Signal Cytokine IL-12 Rescues the Anti-viral Function of Exhausted HBV-specific CD8 T cells. PLOSPathogens (in Press 2012).
  • Tanwar, S., Trembling, P., Guha, I.N., Parkes, J., Kaye, P., Burt, A.D., Ryder, S.D., Aithal, G.P., Day, C.P.,  Rosenberg, W.M. Validation and clinical utility of PIIINP, a single biomarker for the detection and assessment of non-alcoholic steatohepatitis or advanced fibrosis in patients with non-alcoholic fatty liver disease. Hepatology 57 (1), 103-111. doi:10.1002/hep.26030.
  • Deuffic-Burban, S., Deltenre, P., Buti, M., Stroffolini, T., Parkes, J., Mhlberger, N., Uwe Siebert, Moreno, C., Hatzakis, A., Rosenberg, W., Zeuzem, S., Mathurin, P. Predicted Effects of Treatment for HCV Infection Vary Among European Countries. Gastroenterology 143 (4). doi:10.1053/j.gastro.2012.05.054.
  • Wahl, K., Manns, M. P., Bantel, H., Rosenberg, W., Vaske, B., Schulze-Osthoff, K., & Bahr, M. J. (2012). Biopsy-Controlled Liver Fibrosis Staging Using the Enhanced Liver Fibrosis (ELF) Score Compared to Transient Elastography. PLoS ONE, 7 (12). doi:10.1371/journal.pone.0051906
  • Tanwar, S., Wright, M., Foster, G. R., Ryder, S. D., Mills, P. R., Cramp, M. E., . . . Rosenberg, W. M. (2012, February 14). Randomized clinical trial: a pilot study investigating the safety and effectiveness of an escalating dose of peginterferon -2a monotherapy for 48 weeks compared with standard clinical care in patients with hepatitis C cirrhosis.. Eur J Gastroenterol Hepatol.  doi:10.1097/MEG.0b013e3283513e69