Prof Fontana is the director of the University College London (UCL) Cardiac Magnetic Resonance (CMR) unit at the Royal Free Hospital.

She is Professor of cardiology and honorary consultant aardiologist at the National Amyloidosis Centre, division of medicine, UCL, where she is deputy head of center and deputy clinical lead. She obtained her medical degree and qualifications as a cardiologist at the University of Pisa.

She was appointed Director of the UCL CMR unit in 2015, which she founded, and professor of cardiology at UCL in 2020. She was awarded with an intermediate fellowship from the British Heart Foundation in 2018.

Prof Fontana is the recipient of numerous awards, including the Michael Davies Early Career Award in 2021 and the BHF Fellow of the year award in 2022.

Her major clinical and research interests are in the delivery of efficient and effective care for patients with amyloidosis, with a particular focus on new technologies: imaging and drugs.

Prof Fontana's research interests are amyloidosis, cardiac magnetic resonance, and drug development.